On behalf of the Santa Maria Valley Chamber of Commerce and Visitor & Convention Bureau, and its Economic Development Commission, Welcome! The City of Santa Maria is located in California’s Central Coast Wine Country between Santa Barbara and San Luis Obispo. Those fortunate enough to relocate to this peaceful valley will find friendly neighbors, a growing business sector, world-famous Santa Maria Style barbecue, and fabulous California wines. For information on hotels, retirement, healthcare, commercial and residential relocation, economic development services, and demographics on Santa Maria, please contact the Santa Maria Valley Chamber of Commerce and Visitor & Convention Bureau.